| Wang CC |
------>authors3_c=None ------>paper_class1=1 ------>Impact_Factor=1.069 ------>paper_class3=2 ------>paper_class2=1 ------>vol=25 ------>confirm_bywho=kyhsu ------>insert_bywho=crystal ------>Jurnal_Rank=64.3 ------>authors4_c=None ------>comm_author= ------>patent_EDate=None ------>authors5_c=None ------>publish_day=None ------>paper_class2Letter=None ------>page2=2931 ------>medlineContent= ------>unit=G0100 ------>insert_date=20041113 ------>iam=1 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN=None ------>authors_c=None ------>score=500 ------>journal_name=Biomed. Chromatogr ------>paper_name=Photolysis of NSAIDs. IV. Photoproducts of Zomepirac Determined by LC-ESI-MS ------>confirm_date=20051220 ------>tch_id=088003 ------>pmid=15386573 ------>page1=2926 ------>fullAbstract=A sample of 10 mm zomepirac in methanol was photo-irradiated with a Hanovia 200 W high-pressure quartz Hg lamp for 14 days. In total, four photoproducts were observed from the HPLC chromatogram. The preparative HPLC included an YMC-Pack Pro C18 column (250 x 20 mm i.d.), a mobile phase of CH3CN-CH3OH-1%HOAc (10:60:30, v/v/v), and UV detection at 254 nm. The most probable structures of the four photoproducts were determined by LC-MS. Two major photoproducts were separated, and their structures were further confirmed by the spectroscopic methods. A reaction scheme of zomepirac was proposed that the photochemical reaction routes occur mainly via bond fission between carbonyl-pyrrolyl groups (alpha-cleavage of a ketone), and decarboxylation followed by oxidation with singlet oxygen to produce an aldehyde. ------>tmu_sno=None ------>sno=10334 ------>authors2=Chen FA ------>authors3=Chen CJ ------>authors4=Chao SH ------>authors5=Wu AB ------>authors6= ------>authors6_c=None ------>authors=Wang CC ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c=None ------>publish_area=None ------>updateTitle=Photolysis of NSAIDs. IV. Photoproducts of zomepirac determined by LC-ESI-MS. ------>language=1 ------>check_flag=None ------>submit_date=None ------>country=None ------>no= ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2004 ------>submit_flag=None ------>publish_month=None |