| Huang RL |
------>authors3_c=None ------>paper_class1=1 ------>Impact_Factor=None ------>paper_class3=2 ------>paper_class2=1 ------>vol=17 ------>confirm_bywho=hsu0320 ------>insert_bywho=hsu0320 ------>Jurnal_Rank=None ------>authors4_c=None ------>comm_author= ------>patent_EDate=None ------>authors5_c=None ------>publish_day=None ------>paper_class2Letter=None ------>page2=453 ------>medlineContent= ------>unit=G0200 ------>insert_date=20050414 ------>iam=5 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN=None ------>authors_c=None ------>score=312 ------>journal_name=Phytotherapy Research ------>paper_name=Phyllanthus species for anti-human hepatitis B virus in vitro ------>confirm_date=20050414 ------>tch_id=074001 ------>pmid=12748977 ------>page1=447 ------>fullAbstract=Using an HBV-producing cell line and inhibition of the expression of the HBsAg and HBeAg as antiviral indicators, a study was conducted on 25 compounds isolated from four Phyllanthus (Euphorbiaceae) plants, including P. amarus Schum. & Thonn., P. multi florus Willd., P. tenellus Roxb. and P. virgatus Forst. f. It was found that niranthin (1), nirtetralin (3), hinokinin (5) and geraniin (13) at the non-cytotoxic concentration of 50 micro m, suppressed effectively both HBsAg and HBeAg expression, with the highest inhibition at 74.3%, 45.3%; 69.6%, 33.9%; 68.1%, 52.3%; 32.1%, 46.6%, respectively. Of these, niranthin (1) showed the best anti-HBsAg activity, while the most potent anti-HBeAg activity was observed with hinokinin (5). ------>tmu_sno=None ------>sno=11009 ------>authors2=Huang YL ------>authors3=Ou JC ------>authors4=Chen CC ------>authors5=Hsu FL ------>authors6=Chang CM ------>authors6_c=None ------>authors=Huang RL ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c=None ------>publish_area=None ------>updateTitle=Screening of 25 compounds isolated from Phyllanthus species for anti-human hepatitis B virus in vitro. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no= ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2003 ------>submit_flag=None ------>publish_month=None |