| Tang CH |
------>authors3_c=None ------>paper_class1=1 ------>Impact_Factor=None ------>paper_class3=1 ------>paper_class2=1 ------>vol=17 ------>confirm_bywho=elsahsu ------>insert_bywho=cyang ------>Jurnal_Rank=None ------>authors4_c=None ------>comm_author=1 ------>patent_EDate=None ------>authors5_c=None ------>publish_day=None ------>paper_class2Letter=None ------>page2=245 ------>medlineContent= ------>unit=E0800 ------>insert_date=20050729 ------>iam=2 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN=None ------>authors_c=None ------>score=-294 ------>journal_name=Tzu Chi Medical Journal ------>paper_name=A comparative study of clinical severity scoring systems in ICUs in Taiwan ------>confirm_date=20050801 ------>tch_id=087013 ------>pmid=19237903 ------>page1=239 ------>fullAbstract=OBJECTIVE: To determine the prognostic value of day 1 urine excretion of cadmium (1st DUE-Cd) for predicting outcomes in intensive care unit (ICU) patients. DESIGN: Prospective study. SETTING: ICUs in Chang Gung Memorial Hospital, Lin-Kou Medical Center, Taiwan, ROC. PATIENTS: Two hundred one ICU patients. INTERVENTIONS: Urine and blood samples were taken within 24 hours after admission. MEASUREMENTS AND MAIN RESULTS: Disease severity, hospital mortality, and number of organ failures were evaluated in each medical ICU patient. Stepwise multiple linear regression analysis indicated that a history of chronic hepatitis, serum albumin, and glutamic-pyruvic transaminase were significantly related to 1st DUE-Cd after adjusting for other related variables. Cox multivariate analysis revealed that serum blood urea nitrogen level and ICU 1st DUE-Cd were significantly related to hospital mortality after other risk factors and scoring systems were adjusted. Each 1-microg increase in ICU 1st DUE-Cd was associated with a 7% increase in hospital mortality rate. All patients with poisoning magnitude of cadmium excretion (>10 microg/day) died, except one and those with normal cadmium excretion survived. Chi-square values of the Hosmer-Lemeshow goodness-of-fit test were 6.936 (p = 0.544), and area under the receiver operating characteristic curve was 0.868 (95% confidence intervals: 0.82-0.92) for ICU 1st DUE-Cd. CONCLUSIONS: The ICU 1st DUE-Cd may predict hospital mortality in critically ill medical patients. Because of excess mortality and relatively small sample size, the predictive role of DUE-Cd needs further external validation. ------>tmu_sno=None ------>sno=11620 ------>authors2=Yang CM ------>authors3=Chuang CY ------>authors4=Chang ML ------>authors5=Huang YC ------>authors6=Huang CF ------>authors6_c=None ------>authors=Tang CH ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c=None ------>publish_area=None ------>updateTitle=Cadmium excretion predicting hospital mortality and illness severity of critically ill medical patients. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=4 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2005 ------>submit_flag=None ------>publish_month=None |