| Chen RN |
------>authors3_c=None ------>paper_class1=1 ------>Impact_Factor=None ------>paper_class3=2 ------>paper_class2=1 ------>vol=26 ------>confirm_bywho=chiueh ------>insert_bywho=mingsheu ------>Jurnal_Rank=None ------>authors4_c=None ------>comm_author=1 ------>patent_EDate=None ------>authors5_c=None ------>publish_day=None ------>paper_class2Letter=None ------>page2=4235 ------>medlineContent= ------>unit=G0000 ------>insert_date=20050811 ------>iam=3 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN=None ------>authors_c=None ------>score=500 ------>journal_name=Biomaterials ------>paper_name=Characterization of collagen matrices crosslinked using microbial transglutaminase ------>confirm_date=20050829 ------>tch_id=075001 ------>pmid=15683645 ------>page1=4229 ------>fullAbstract=In search of a new approach for crosslinking collagen-based biomaterials, we examined the effect of microbial transglutaminase (MTGases) as a crosslinking reagent on collagenous matrices made from porcine type I collagen. As the results revealed, MTGase exhibited a crosslinking action that raised the viscosity of the collagen solution. Matrices crosslinked with MTGase at the low pH values of pH 3 and 4 exhibited higher tensile strengths than those at high pH values. In comparison with untreated matrices, the denaturation temperatures of the corresponding matrices shifted toward higher temperatures. These enzyme-catalyzed crosslinked matrices were proven by MTT assay to be non-cytotoxic. In conclusion, this enzymatic method of using MTGase provides an alternative potential way for crosslinking collagen-based matrices. ------>tmu_sno=None ------>sno=11648 ------>authors2=Ho HO ------>authors3=Sheu MT ------>authors4= ------>authors5= ------>authors6= ------>authors6_c=None ------>authors=Chen RN ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c=None ------>publish_area=None ------>updateTitle=Characterization of collagen matrices crosslinked using microbial transglutaminase. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no= ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2005 ------>submit_flag=None ------>publish_month=None |