Liu HC, Hu CJ |
------>authors3_c=None ------>paper_class1=1 ------>Impact_Factor=2.493 ------>paper_class3=2 ------>paper_class2=1 ------>vol=21 ------>confirm_bywho=leehorng ------>insert_bywho=cmbsycl ------>Jurnal_Rank=28.8 ------>authors4_c=None ------>comm_author=1 ------>patent_EDate=None ------>authors5_c=None ------>publish_day=None ------>paper_class2Letter=None ------>page2=161 ------>medlineContent= ------>unit=E0600 ------>insert_date=20060125 ------>iam=7 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN=None ------>authors_c=None ------>score=500 ------>journal_name=Dement Geriatr Cogn Disord. ------>paper_name=Proteomic Identification of Lower Apolipoprotein A-I in Alzheimer's Disease. ------>confirm_date=20060207 ------>tch_id=083006 ------>pmid=16391478 ------>page1=155 ------>fullAbstract=Many researches have been trying to find the potential biomarkers for Alzheimer~s disease (AD). We hereby used the proteomics method to search for protein expression differences in the serum between AD patients and controls. We enrolled 59 AD patients and 74 age- and sex-matched controls in this study. Ten AD patients and 10 controls were selected for proteomic analysis. Apolipoprotein A-I (ApoA-I) was found to have a lower expression in the AD group by a proteomics two-dimensional gel electrophoresis study. We further measured the serum ApoA-I level which was significantly lower in the AD patients (112.29 +/- 21.33 mg/dl) in comparison to the controls (144.53 +/- 19.91 mg/dl; p < 0.0002). Lower serum ApoA-I levels might be a potential biomarker for AD. ------>tmu_sno=None ------>sno=12445 ------>authors2=Chang JG ------>authors3=Sung SM ------>authors4=Lee LS ------>authors5=Yuan RY ------>authors6=Leu SJ ------>authors6_c=None ------>authors=Liu HC, Hu CJ ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c=None ------>publish_area=None ------>updateTitle=Proteomic identification of lower apolipoprotein A-I in Alzheimer~s disease. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=3 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2006 ------>submit_flag=None ------>publish_month=None |