Taipei Medical University

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Wu CC
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------>insert_date=20060203
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------>journal_name=Acta Anesthesiologica Taiwanica
------>paper_name=Effect of Doxapram on Sevoflurane Anesthesia Arousal and Bispectral Index
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------>pmid=16895622
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------>fullAbstract=BACKGROUND AND OBJECTIVE: To evaluate and compare the effect of two clinically available central nervous system stimulants, namely doxapram and aminophylline on arousal from sevoflurane anaesthesia and bispectral index. METHODS: This randomized, double-blind, placebo-controlled, prospective study was conducted in 90 adult females, ASA I-II, scheduled for elective lower abdominal surgeries at Taipei Medical University Hospital. At 5 min before the completion of surgery, under sevoflurane anaesthesia, patients were divided into three groups to receive doxapram 1 mg kg(-1), aminophylline 2 mg kg(-1) or saline placebo intravenous. Standard vital signs, end-tidal CO(2), end-expiratory sevoflurane concentration, bispectral index and neuromuscular blockade were measured plus clinical parameters of recovery from general anaesthesia. RESULTS: Compared with the control group, patients receiving doxapram or aminophylline showed a similarly faster recovery from sevoflurane anaesthesia correlated with increase in bispectral index. CONCLUSION: Intravenous administration of doxapram 1 mg kg(-1) or aminophylline 2 mg kg(-1) hastened the early recovery from sevoflurane anaesthesia. The arousal effect of aminophylline and doxapram appears to be similar.
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------>authors2=Lin CS
------>authors3=Mok MS
------>authors4=Chen TL
------>authors5=Chen JY
------>authors6=Wu GJ,Wen YR
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------>authors=Wu CC
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------>updateTitle=Doxapram and aminophylline on bispectral index under sevoflurane anaesthesia: a comparative study.
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------>no=CO4
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------>publish_year=2005
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z