Taipei Medical University

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Liu HC,
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------>journal_name=J Neuroimmunol
------>paper_name=Immunological variables in acute mania of bipolar disorder.
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------>fullAbstract=OBJECTIVE: The authors hypothesized that in the majority of HIV-positive patients presenting with mania, the mania is secondary to HIV infection and that its presentation and correlates differ from those of HIV-negative patients with primary mania. METHOD: A comparative cross-sectional study was conducted with HIV-negative and HIV-positive patients admitted to psychiatric wards with acute mania. The authors compared the patients~ psychiatric, physical, and immunological (CD4 cell counts) and other laboratory parameters. Pairwise comparisons were done for the two groups on a number of variables. RESULTS: Of 141 patients who presented with acute mania during a 6-month period and were eligible for the study, 61 met criteria for HIV-related secondary mania. Compared with HIV-negative patients with primary mania, they were older, more cognitively impaired less educated, and more likely to be female. Patients in this group had more manic symptoms: they were more irritable, more aggressive, more talkative, and had higher rates of paranoid delusions, visual hallucinations, and auditory hallucinations. More of the HIV-positive secondary mania group had CD4 counts below 350 cells/mm(3). CONCLUSIONS: Primary mania and HIV-related secondary mania are clinically and immunologically distinct. The relation between secondary mania and depressed CD4 counts suggests that in the setting of an HIV/AIDS epidemic in poor countries, secondary mania may be used as an indicator to initiate highly active antiretroviral therapy.
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------>authors2=Yang YY
------>authors3=Chou YM
------>authors4=Chen KP
------>authors5=Shen WW
------>authors6=Leu SJ
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------>authors=Liu HC,
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------>updateTitle=Primary mania versus HIV-related secondary mania in Uganda.
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------>publish_year=2004
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z