| Tsai RJF |
------>authors3_c=??? ------>paper_class1=1 ------>Impact_Factor=None ------>paper_class3=1 ------>paper_class2=1 ------>vol=38 ------>confirm_bywho=chlin ------>insert_bywho=raytsai ------>Jurnal_Rank=None ------>authors4_c=??? ------>comm_author= ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2=418 ------>medlineContent= ------>unit=E0200 ------>insert_date=20060506 ------>iam=1 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN= ------>authors_c=??? ------>score=0 ------>journal_name=Reprinted From Transaction of Ophthalmological Society of the Republic of China ------>paper_name=A Successful Treatment of Neurotrophic Ulcer With Amniotic Membrane Transplantation ------>confirm_date=20060516 ------>tch_id=092157 ------>pmid=15256996 ------>page1=413 ------>fullAbstract=PURPOSE: To determine if multilayer amniotic membrane transplantation (AMT) is useful in the treatment of corneal perforations, and in particular to assess to what extent efficacy is affected by perforation size. METHODS: Fifteen patients (15 eyes) with corneal perforations of different sizes were divided into 3 groups: group A (microperforation, 6 eyes), group B (0.5-1.5 mm, 4 eyes), and group C (>1.5 mm, 5 eyes). The corneal perforation was caused by autoimmunity-related ulcer (3 eyes), neurotrophic ulcer (9 eyes), infectious keratitis (1 eye), or postkeratoplasty ulcer (2 eyes). Two layers of AM (for microperforations) or 3-4 layers (for the other groups) were trimmed to the size of the ulcer and sutured in place with interrupted 10-0 nylon sutures. In all cases, a bandage contact lens was then applied. RESULTS: Mean epithelialization time was 3.7 weeks (range 2-6). Mean time to recovery of corneal stroma thickness was 10.1 weeks (range 7-15). In all cases, ocular inflammation subsided within 2-5 weeks. The treatment was judged successful in 73% (11/15) of eyes. Three of the 4 unsuccessful treatments were of perforations 3 mm or more in diameter; of the 5 eyes with perforations of more than 1.5 mm in diameter, only 2 were treated successfully. CONCLUSIONS: These results suggest that multilayer AMT is effective for treating corneal perforations with diameter less than 1.5 mm. The technique may be a good alternative to penetrating keratoplasty, especially in acute cases in which graft rejection risk is high. ------>tmu_sno=None ------>sno=13838 ------>authors2=Li Chia-Yun ------>authors3=Huang CM ------>authors4=Lai HC ------>authors5= ------>authors6= ------>authors6_c= ------>authors=Tsai RJF ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c=??? ------>publish_area=0 ------>updateTitle=Multilayer amniotic membrane transplantation in the treatment of corneal perforations. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=3 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=1999 ------>submit_flag=None ------>publish_month=1 |