Taipei Medical University

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Lin JW
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------>journal_name=Surgical Neurology
------>paper_name=Survey of traumatic intracranial hemorrhage in Taiwan.
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------>fullAbstract=The correlations between D-dimer and Glasgow Coma Scale (GCS), pupillary light reflex, distance of midline shift on brain computed tomography (CT), and Glasgow Outcome Score (GOS) in patients with trauma/non-trauma intracranial hemorrhage (ICH) are not consistent in studies. Ninety-eight traumatic and 59 non-traumatic ICH patients were studied. Pre-existing venous thrombosis, recent surgery, drug use (aspirin or coumadin), or malignancy, were excluded. D-dimer level was estimated within hours after acute insult, and statistical analyses were used for comparisons between groups. Traumatic ICH patients had higher D-dimer levels than controls (2984 vs. 256 microg/l; P = 0.001). The GCS, midline shift on brain CT, pupillary reflex, and GOS at 3 months were significantly correlated with high D-dimer value in traumatic patients (individual P < 0.001), but not in the non-traumatic group. Using receiver-operating characteristic curve (ROC), the cutoff point was 1496 microg/l, with sensitivity and specificity of 100% and 83%, respectively. D-dimer > or =1496 microg/l predicted a poor outcome [adjusted odds ratio (OR) 14.44, 95% CI 1.16-179.27; P = 0.038]. A high D-dimer level is associated with a poor outcome in patients with traumatic ICH. It can be used in addition to neurological assessment to predict the outcome.
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------>authors2=Tsai SH
------>authors3=Tsai WC
------>authors4=Chiu WT
------>authors5=Chu SF
------>authors6=Lin CM, Yang CM, Hung CC
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------>authors=Lin JW
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------>updateTitle=Correlation of a high D-dimer level with poor outcome in traumatic intracranial hemorrhage.
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------>no=Suppl2
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------>publish_year=2006
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------>publish_month=11
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z