Liu IM |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=1.628 ------>paper_class3=2 ------>paper_class2=1 ------>vol=71 ------>confirm_bywho=hsu0320 ------>insert_bywho=hsu0320 ------>Jurnal_Rank=29.2 ------>authors4_c= ------>comm_author= ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2=621 ------>medlineContent= ------>unit=G0200 ------>insert_date=20070330 ------>iam=4 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN= ------>authors_c= ------>score=500 ------>journal_name=Planta Medica ------>paper_name=Myricetin as the Active Principle of Abelmoschus moschatus to Lower Plasma Glucose in Streptozotocin-Induced Diabetic Rats ------>confirm_date=20070331 ------>tch_id=074001 ------>pmid=16041646 ------>page1=617 ------>fullAbstract=The antihyperglycemic action of myricetin, purified from the aerial part of Abelmoschus moschatus (Malvaceae), was investigated in streptozotocin-induced diabetic rats (STZ-diabetic rats). Bolus intravenous injection of myricetin decreased the plasma glucose concentrations in a dose-dependent manner in STZ-diabetic rats. Myricetin at the effective dose (1.0 mg/kg) significantly attenuated the increase of plasma glucose induced by an intravenous glucose challenge test in normal rats. A stimulatory effect of myricetin on glucose uptake of the soleus muscles isolated from STZ-diabetic rats was obtained in a concentration-dependent manner from 0.01 to 10.0 micromol/L. The increase of glucose utilization by myricetin was further characterized using the enhancement of glycogen synthesis in isolated hepatocytes of STZ-diabetic rats. These results suggest that myricetin has an ability to enhance glucose utilization to lower plasma glucose in diabetic rats lacking insulin. ------>tmu_sno=None ------>sno=14776 ------>authors2=Liou SS ------>authors3=Lan TW ------>authors4=Hsu FL ------>authors5=Cheng JT ------>authors6= ------>authors6_c= ------>authors=Liu IM ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Myricetin as the active principle of Abelmoschus moschatus to lower plasma glucose in streptozotocin-induced diabetic rats. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no= ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2005 ------>submit_flag=None ------>publish_month=1 |