| Hsing CH |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=2.012 ------>paper_class3=2 ------>paper_class2=1 ------>vol=35 ------>confirm_bywho=jschu ------>insert_bywho=sschuang ------>Jurnal_Rank=60.2 ------>authors4_c= ------>comm_author= ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2=52 ------>medlineContent= ------>unit=E0102 ------>insert_date=20070421 ------>iam=5 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN= ------>authors_c= ------>score=500 ------>journal_name=Cytokine ------>paper_name=Tissue microarray analysis of interleukin-20 expression. ------>confirm_date=20070421 ------>tch_id=094004 ------>pmid=16908179 ------>page1=44 ------>fullAbstract=Knowledge about the biological functions and clinical implications of interleukin (IL)-20, a recently discovered cytokine in the IL-10 family, is still incomplete. Our aim was to determine the distribution of IL-20 expression and to delineate the cell types that express IL-20 in healthy and neoplastic tissue, because this information will significantly affect the exploration of its pathophysiological roles. We used tissue microarray technology and an immunohistochemical survey using an anti-IL-20 monoclonal antibody to examine IL-20 expression in 36 non-neoplastic and 14 neoplastic tissues. IL-20 protein was positively stained in 30 non-neoplastic tissue types and five major cell types: epithelial cells, myoepithelial cells, endothelial cells, macrophages, and skeletal muscle cells. We also found that several types of tumor cells stained positive for IL-20, especially in squamous cell carcinoma of the skin, tongue, esophagus, and lung. Our data provide valuable references for further investigation of the biological functions and clinical implications of IL-20 in humans. ------>tmu_sno=None ------>sno=15127 ------>authors2=Ho CL ------>authors3=Chang LY ------>authors4=Lee YL ------>authors5=Chuang SS ------>authors6=Chang MS ------>authors6_c= ------>authors=Hsing CH ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Tissue microarray analysis of interleukin-20 expression. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no= ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2006 ------>submit_flag=None ------>publish_month=6 |