| Su CL. |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=0.474 ------>paper_class3=2 ------>paper_class2=1 ------>vol=106 ------>confirm_bywho=chshih43 ------>insert_bywho=clsu ------>Jurnal_Rank=76.2 ------>authors4_c= ------>comm_author= ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2=211 ------>medlineContent= ------>unit=E0400 ------>insert_date=20070503 ------>iam=1 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN= ------>authors_c= ------>score=442 ------>journal_name=J Formos.Med Assoc ------>paper_name=Domiciliary Positive Expiratory Pressure on Pulmonary Function and Exercise Capacity in Patients with Chronic Obstructive Pulmonary Disease ------>confirm_date=20070503 ------>tch_id=092062 ------>pmid=17389164 ------>page1=204 ------>fullAbstract=BACKGROUND/PURPOSE: This study assessed how positive expiratory pressure (PEP) affected pulmonary function, functional capacity, and subjective cough difficulty in individuals with chronic obstructive pulmonary diseases (COPD). METHODS: This was a prospective, randomized, controlled study. Subjects were recruited from an outpatient department at a university hospital. Thirty-two patients with COPD were allocated to either PEP + FET (forced expiratory technique) group (n = 16) or FET only group (n = 16). Subjects in PEP + FET and FET groups were in a clinically stable condition before and during the study. Subjects in the PEP + FET group received PEP breathing using a mouth adjunct to FET, and the FET group was administered FET for 4 weeks only. Patients received weekly follow-up during the study period. Pulmonary function, 6-minute walk tests, and subjective cough difficulty scores were measured before and after the 4-week interventions. RESULTS: Subjects in the PEP + FET group had a significantly increased diffusing capacity (DLCO) compared to preintervention (p < 0.05) and after intervention in the FET group (p < 0.05). DLCO significantly increased in the PEP + FET group from 18.0 +/- 7.3 to 20.1 +/- 7.2 mL/min/mmHg. The 6-minute walking distance (6MWD) also increased significantly from 516.8 +/- 94.1 to 570.6 +/- 60.4 m in the PEP + FET group (p < 0.001) after intervention, compared to that for the FET group (p < 0.05). Additionally, the PEP + FET group had significantly lower cough difficulty scores compared to those at baseline and in the FET group. CONCLUSION: Four-week PEP therapy as an adjunct to FET further enhanced DLCO and 6MWD, and reduced cough difficulty compared to FET only in COPD patients with mucus hypersecretion. ------>tmu_sno=None ------>sno=15484 ------>authors2=Chiang LL ------>authors3=Yu CT ------>authors4=Kuo HP ------>authors5=LIn HC ------>authors6= ------>authors6_c= ------>authors=Su CL. ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Domiciliary positive expiratory pressure improves pulmonary function and exercise capacity in patients with chronic obstructive pulmonary disease. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=3 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2007 ------>submit_flag=None ------>publish_month=1 |