Lin HC |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=None ------>paper_class3=3 ------>paper_class2=1 ------>vol=70 ------>confirm_bywho=nwkuo ------>insert_bywho=henry11111 ------>Jurnal_Rank=None ------>authors4_c= ------>comm_author= ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2=76 ------>medlineContent= ------>unit=E0800 ------>insert_date=20070831 ------>iam=1 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN= ------>authors_c= ------>score=89 ------>journal_name=Psychosomatic Medicine ------>paper_name=No Higher Risk of Myocardial Infarction in a Six-Year Follow Up of ------>confirm_date=20080711 ------>tch_id=090053 ------>pmid=17054593 ------>page1=73 ------>fullAbstract=AIMS: To determine the prognosis of patients with Type 1 or Type 2 diabetes, 6 years after screening for silent myocardial ischaemia (SMI). METHODS: Two hundred and three asymptomatic patients with diabetes underwent systematic SMI screening. From the results of this screening, they were allocated to one of three groups: patients (n = 171) with negative screening; patients (n = 32) with positive screening; and patients (n = 21) with positive screening and coronary stenosis. Six years after the initial assessment, all patients were re-assessed. All events [death, cardiac death, non-fatal major cardiac events (NFMCEs)--acute myocardial infarction, ventricular rhythm disorders, heart failure, unstable angina] were recorded. RESULTS: Fifteen patients were lost to follow-up. Patients (n = 20) with positive SMI screening and coronary stenosis had a higher risk of NFMCEs (35% vs. 7%, P < 0.001), and a higher mortality rate (35% vs. 15%, P < 0.05) compared with patients (n = 157) with negative screening. SMI-positive patients (n = 31) had a higher NFMCE rate compared with negative SMI screening patients, although overall mortality rate was no different. Cancer was the leading cause of death (36.4%). In multivariate analysis, major cardiac events (cardiac death and NFMCE) were related to baseline age, body mass index and coronary stenosis (P < 0.01). CONCLUSIONS: Patients with diabetes and SMI have a very poor prognosis as assessed by cardiac events or death, especially in the presence of coronary stenosis. ------>tmu_sno=None ------>sno=15951 ------>authors2=Tsai SY ------>authors3=Lee HC ------>authors4= ------>authors5= ------>authors6= ------>authors6_c= ------>authors=Lin HC ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Six-year follow-up of a cohort of 203 patients with diabetes after screening for silent myocardial ischaemia. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=1 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2008 ------>submit_flag=None ------>publish_month=1 |