Huang GC |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=2.157 ------>paper_class3=2 ------>paper_class2=1 ------>vol=7 ------>confirm_bywho=shiemin ------>insert_bywho=b681036 ------>Jurnal_Rank=47.2 ------>authors4_c= ------>comm_author= ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2=1063 ------>medlineContent= ------>unit=E0100 ------>insert_date=20070910 ------>iam=2 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN=1567-5769 ------>authors_c= ------>score=-124 ------>journal_name=International Immunopharmacology ------>paper_name=Wogonin but not Nor-wogonin inhibits lipopolysaccharide and lipoteichoicacid-induced iNOS gene expression and NO production in macrophages ------>confirm_date=20070911 ------>tch_id=089101 ------>pmid=19829679 ------>page1=1054 ------>fullAbstract=OBJECTIVE:To study the flavonoids of Scutellaria baicalensis and their bioactivities. METHODS: Chromatographic methods were used to separate compounds, spectral methods were used to determine the structures and bioactivities of the flavonoids were screened in several models in vitro. RESULTS: Nine compounds were isolated and identified as baicalein (1), wogonin (2), oroxylin A (3), 5, 7, 2~, 6~-tetrahydroxyflavone (4), viscidulin III (5), baicalin (6), wogonoside (7), oroxylin A-7-O-beta-D-glucuronide (8) and chrysin-6-C-alpha-L-arabinopyranosyl-8-C-beta-D-glucopyranoside (9). CONCLUSION: Baicalein had good anti-bacteria activity, and some compounds showed inhibiting activity against IL-1beta converting enzyme. The 13C NMR data of compounds 9 were assigned correctly by 2D nuclear magnetic resonance (NMR). ------>tmu_sno=None ------>sno=15981 ------>authors2=ChowJM ------>authors3=Shen SC ------>authors4=Yang LY ------>authors5=Lin CW ------>authors6=Chen YC ------>authors6_c= ------>authors=Huang GC ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=[Flavonoids from Scutellaria baicalensis and their bioactivities.] ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=8 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2007 ------>submit_flag=None ------>publish_month=8 |