| Lu HF |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=1.273 ------>paper_class3=2 ------>paper_class2=1 ------>vol=21 ------>confirm_bywho=leehorng ------>insert_bywho=yangyuan ------>Jurnal_Rank=68.4 ------>authors4_c= ------>comm_author= ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2=289 ------>medlineContent= ------>unit=E0310 ------>insert_date=20071120 ------>iam=4 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN= ------>authors_c= ------>score=500 ------>journal_name=in vivo ------>paper_name=(-)-Menthol inhibits WEHI-3 leukemia cells in vitro and in vivo ------>confirm_date=20071127 ------>tch_id=083003 ------>pmid=17436578 ------>page1=285 ------>fullAbstract=(-)-Menthol ([1-alpha]-5-methyl-2-[1-methylethyl]-cyclohexanol), is a widely used flavoring ingredient in mouthwash, foods, toothpaste and cigarettes. The studies reported here revealed that (-)-menthol induced cytotoxicity against murine leukemia WEHI-3 cells in vitro in a dose-dependent manner. The effects of (-)-menthol on WEHI-3 cells in vivo (BALBIc mice) were also examined, and it was observed that the Mac-3 and CD11b markers were decreased, indicating inhibition of differentiation of the precursor of macrophage and granulocyte. The weights of liver and spleen samples from mice treated with (-)-menthol were found to be decreased compared to untreated animals. ------>tmu_sno=None ------>sno=16197 ------>authors2=Liu JY ------>authors3=Hsueh SC ------>authors4=Yang YY ------>authors5=Yang JS ------>authors6=Tan TW, Kok LF, Lu CC, Lan SH, Wu SY, et al., ------>authors6_c= ------>authors=Lu HF ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=(-)-Menthol inhibits WEHI-3 leukemia cells in vitro and in vivo. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=2 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2007 ------>submit_flag=None ------>publish_month=3 |