| Ruland S |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=5.690 ------>paper_class3=2 ------>paper_class2=1 ------>vol=67 ------>confirm_bywho=shiemin ------>insert_bywho=hsuc ------>Jurnal_Rank=4.1 ------>authors4_c= ------>comm_author= ------>patent_EDate=None ------>authors5_c= ------>publish_day=22 ------>paper_class2Letter=None ------>page2=571 ------>medlineContent= ------>unit=E0100 ------>insert_date=20071129 ------>iam=7 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN= ------>authors_c= ------>score=500 ------>journal_name=Neurology ------>paper_name=Predictors of Recurrent Stroke in African Americans ------>confirm_date=20071129 ------>tch_id=091141 ------>pmid=16924005 ------>page1=567 ------>fullAbstract=BACKGROUND: Stroke incidence and mortality are disproportionately higher among African Americans than among whites. OBJECTIVE: To describe the recurrent stroke characteristics and determine the predictability of known vascular risk factors for stroke recurrence in African Americans. METHODS: The authors followed 1,809 African Americans in the African-American Antiplatelet Stroke Prevention Study with recent noncardioembolic ischemic stroke for recurrent stroke, recurrent stroke subtype, and disability. RESULTS: Of the subjects, 10.6% experienced a recurrent stroke during follow-up. The mean interval between eligibility and recurrent stroke was 325 days (median 287 days, SD = 224 days). Stroke recurrence resulted in an average 1.5-point increase in the National Institute of Health Stroke Scale (p < 0.001) and a 3.5-point decrease in modified Barthel Index (p < 0.001). Of previously nondisabled subjects, 48% became disabled or died after stroke recurrence (p < 0.0001). Longitudinal analysis resulted in a hazard for recurrent stroke for each 10-mm Hg increase in systolic blood pressure of 1.103 (95% CI: 1.031 to 1.179, p = 0.004), pulse pressure 1.123 (95% CI: 1.041 to 1.213, p = 0.003), and mean arterial pressure 1.123 (95% CI: 1.001 to 1.260, p = 0.048). Multivariate analysis revealed increases in the recurrent stroke hazard for increases in baseline Glasgow Outcome Score (1.449, 95% CI: 1.071 to 1.961, p = 0.016) and increases in longitudinal pulse pressure (1.009, 95% CI: 1.001 to 1.017, p = 0.029). CONCLUSION: Recurrent stroke leads to disability and disability predicts recurrent stroke. Hypertension is the most predictive modifiable stroke risk factor. ------>tmu_sno=None ------>sno=16291 ------>authors2=Richardson D ------>authors3=Hung E ------>authors4=Brorson JR ------>authors5=Cruz-Flores S ------>authors6=Felton WL 3rd, Ford-Lynch G, Helgason C, Hsu C, ------>authors6_c= ------>authors=Ruland S ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Predictors of recurrent stroke in African Americans. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=4 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2006 ------>submit_flag=None ------>publish_month=8 |