Taipei Medical University

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Huang GC
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------>insert_date=20071231
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------>ISSN=1567-5769
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------>journal_name=International Immunopharmacology
------>paper_name=Wogonin but not Nor-wogonin inhibits lipopolysaccharide and lipoteichoic acid-induced iNOS gene expression and NO production in macrophages.
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------>fullAbstract=OBJECTIVE:To study the flavonoids of Scutellaria baicalensis and their bioactivities. METHODS: Chromatographic methods were used to separate compounds, spectral methods were used to determine the structures and bioactivities of the flavonoids were screened in several models in vitro. RESULTS: Nine compounds were isolated and identified as baicalein (1), wogonin (2), oroxylin A (3), 5, 7, 2~, 6~-tetrahydroxyflavone (4), viscidulin III (5), baicalin (6), wogonoside (7), oroxylin A-7-O-beta-D-glucuronide (8) and chrysin-6-C-alpha-L-arabinopyranosyl-8-C-beta-D-glucopyranoside (9). CONCLUSION: Baicalein had good anti-bacteria activity, and some compounds showed inhibiting activity against IL-1beta converting enzyme. The 13C NMR data of compounds 9 were assigned correctly by 2D nuclear magnetic resonance (NMR).
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------>authors2=Chow JM
------>authors3=Shen SC
------>authors4=Yang LY
------>authors5=Lin CW
------>authors6=Chen YC
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------>authors=Huang GC
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------>updateTitle=[Flavonoids from Scutellaria baicalensis and their bioactivities.]
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------>no=8
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------>publish_year=2007
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z