| Chen SR |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=0.533 ------>paper_class3=2 ------>paper_class2=1 ------>vol=106 ------>confirm_bywho=kueiru ------>insert_bywho=chii ------>Jurnal_Rank=74.8 ------>authors4_c= ------>comm_author=1 ------>patent_EDate=None ------>authors5_c= ------>publish_day=7 ------>paper_class2Letter=None ------>page2=942 ------>medlineContent= ------>unit=H0200 ------>insert_date=20080122 ------>iam=4 ------>update_date=None ------>author=?? ------>change_event=4 ------>ISSN=0929-6646 ------>authors_c= ------>score=500 ------>journal_name=Journal of the Formosan Medical Association ------>paper_name=Impact of Glycemic Control, disease Duration, and Exercise on Heart Rate Variability in Children with type 1 Diabetes Mellitus ------>confirm_date=20080424 ------>tch_id=084010 ------>pmid=18063515 ------>page1=935 ------>fullAbstract=BACKGROUND/PURPOSE: Type 1 diabetes is commonly associated with autonomic neuropathy. The present study investigated the influences of glycemic control, disease duration (DD), and exercise on autonomic nervous function in children with type 1 diabetes by analysis of their heart rate variability (HRV). METHODS: Seventy-nine type 1 diabetic children were recruited and categorized into four groups by HbA1c of 8% and DD of 4.5 years. HRV parameters as determined by separate frequency domain components (low frequency: LnLF, 0.04-0.15 Hz; high frequency: LnHF, 0.15-0.5 Hz; total power: LnTP, 0.04-0.5 Hz) were measured both at rest and during exercise. Pearson~s correlation, one-way ANOVA, and multiple regressions with stepwise method were used for statistical analysis. RESULTS: While at rest, HbA1c and DD were negatively correlated with all HRV parameters. Both HbA1c and DD were significant predictors in LnTP. However, only HbA1c was a significant predictor in LnLF and LnHF. Type 1 diabetes patients with HbA1c > 8% and DD > 4.5 years had a significantly lower HRV than the other patients. During exercise, HRV reduced significantly and no significant correlation between HbA1c and HRV or between DD and HRV was observed. Also, a significant difference in HRV among the four groups was not demonstrated. The smallest decrement in HRV from resting to exercise were in subjects with HbA1c > 8% and DD > 4.5 years. CONCLUSION: HbA1c was a more dominant predictor for LnTP, LnHF and LnLF than DD in children with type 1 diabetes at rest. HRV reduced significantly from resting to exercise. However, the responses of HRV during exercise differ from the responses of HRV at rest. ------>tmu_sno=None ------>sno=16625 ------>authors2=Lee YJ ------>authors3=Chiu HW ------>authors4=Jeng C ------>authors5= ------>authors6= ------>authors6_c= ------>authors=Chen SR ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Impact of glycemic control, disease duration, and exercise on heart rate variability in children with type 1 diabetes mellitus. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=11 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2007 ------>submit_flag=None ------>publish_month=8 |