| Chang LY |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=3.566 ------>paper_class3=2 ------>paper_class2=1 ------>vol=158 ------>confirm_bywho=leehorng ------>insert_bywho=wuhs ------>Jurnal_Rank=18.8 ------>authors4_c= ------>comm_author= ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2=1042 ------>medlineContent= ------>unit=E0310 ------>insert_date=20080205 ------>iam=7 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN= ------>authors_c= ------>score=500 ------>journal_name=Arch Pediatr Adolesc Med ------>paper_name=Childhood severe acute respiratory syndrome in Taiwan and how to differentiate it from childhood influenza infection. ------>confirm_date=20081008 ------>tch_id=093109 ------>pmid=15520340 ------>page1=1037 ------>fullAbstract=OBJECTIVE: To investigate clinical features and outcomes of children in Taiwan with laboratory-confirmed severe acute respiratory syndrome (SARS) vs those of children with influenza to differentiate the 2 diseases. DESIGN, SETTING, AND PARTICIPANTS: Patients 20 years or younger with clinical, epidemiological, and laboratory evidence of SARS from March to July 2003 vs children with virus culture-confirmed influenza in a 1:1 age- and sex-matched control group. MAIN OUTCOME MEASURES: Rates of symptoms, abnormal laboratory data, and outcomes of recovery, sequelae, or death. RESULTS: The 15 SARS patients (9 girls and 6 boys) had a median age of 17 years (age range, 4-20 years). Nine patients (60%) were infected through household contact, 4 (27%) nosocomially, 1 (7%) through contact with a neighbor, and 1 (7%) after returning from Hong Kong. All 15 patients had fever, 3 (20%) had chills, and 11 (73%) had cough. Only 1 patient (7%) had sputum production; 1 (7%) had rhinorrhea. At presentation, 5 patients (33%) had leukopenia, 6 (40%) had lymphopenia, and 5 (33%) had monocytopenia. All children recovered without sequelae. Children with SARS had significantly lower incidences of rhinorrhea (odds ratio [OR], 0.01; 95% confidence interval [CI], 0.00-0.09), sputum production (OR, 0.10; 95% CI, 0.02-0.63), and sore throat (OR, 0.17; 95% CI, 0.03-0.85) than children with influenza. Both groups had similar incidences of leukopenia or lymphopenia, but SARS patients had a significantly higher incidence of monocytopenia (33% vs 0%, P = .04). CONCLUSIONS: Childhood SARS is usually not fatal. The absence of rhinorrhea and presence of monocytopenia in SARS may distinguish it from influenza. ------>tmu_sno=None ------>sno=16642 ------>authors2=Huang FY ------>authors3=Wu YC ------>authors4=Su IJ ------>authors5=Chiu NC ------>authors6=Chen KT, Wu HS, Lin TH, Peng SF, Kao CL, Lee CY, H ------>authors6_c= ------>authors=Chang LY ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Childhood severe acute respiratory syndrome in Taiwan and how to differentiate it from childhood influenza infection. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no= ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2004 ------>submit_flag=None ------>publish_month=1 |