Taipei Medical University

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Hsu MI
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------>journal_name=Fertil Steril
------>paper_name=Inappropriate gonadotropin secretion in polycystic ovary syndrome
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------>fullAbstract=OBJECTIVE: To evaluate inappropriate gonadotropin secretion in women with polycystic ovary syndrome (PCOS). DESIGN: Retrospective study. SETTING: Academic tertiary center. PATIENT(S): A total of 373 women were classified into three groups: [1] healthy control women (n = 48); [2] women who were positive for PCOS risk factor; and [3] women with PCOS (n = 251). INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Gonadotropin levels, LH-FSH ratio, body mass index, and clinical and/or biochemical presentations of PCOS. RESULT(S): The area under the receiver operating characteristic curve, used to predict PCOS for the LH-FSH ratio, showed similar diagnostic performance to total T and average ovarian volume. The LH-FSH ratio exhibits greater observed accuracy than total T and average ovarian volume for evaluation of women with oligomenorrhea or anovulation. An LH-FSH ratio of >1 presented the best combination of sensitivity and specificity. Body mass index was positively correlated with total T in non-PCOS and PCOS groups; however, body mass index was negatively correlated with LH in PCOS but showed no correlation in non-PCOS subjects. CONCLUSION(S): The LH-FSH ratio is a valuable diagnostic tool in evaluating women with PCOS and oligomenorrhea or anovulation, and an LH-FSH ratio of >1 may be used as a decision threshold. The link between body mass index and LH may provide clues for further understanding the pathological milieu of PCOS.
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------>authors2=Liou TH
------>authors3=Liang SJ
------>authors4=Su HW
------>authors5=Wu CH
------>authors6=Hsu CS
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------>authors=Hsu MI
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------>updateTitle=Inappropriate gonadotropin secretion in polycystic ovary syndrome.
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------>publish_year=2008
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------>publish_month=3
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z