| Lo YJ |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=1.070 ------>paper_class3=2 ------>paper_class2=1 ------>vol=27 ------>confirm_bywho=None ------>insert_bywho=ycliang ------>Jurnal_Rank=73.9 ------>authors4_c= ------>comm_author= ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2=1111 ------>medlineContent= ------>unit=E0310 ------>insert_date=20080315 ------>iam=7 ------>update_date=None ------>author=??? ------>change_event=1 ------>ISSN= ------>authors_c= ------>score=406 ------>journal_name=Rheumatol Int. ------>paper_name=Intra-articular injection of hyaluronate and indomethacin in rabbits with antigen-induced arthritis. 27: 1099-111. ------>confirm_date=None ------>tch_id=089135 ------>pmid=17436002 ------>page1=1099 ------>fullAbstract=Combined effects of hyaluronate and indomethacin in the treatment of rabbits with antigen-induced arthritis (AIA) were evaluated by assessing joint swelling, C-reactive protein (CRP) and prostaglandin E(2) (PGE(2)) levels with periodic intra-articular (ia) injections of hyaluronate alone (HA group) and with either a low or high concentration of indomethacin (LI-HA or HI-HA group). End-point analyses included matrix metalloproteinases-3 (MMP-3) activity and macroscopic and histological joint examinations. Results demonstrated that treatment in LI-HA and HI-HA groups resulted in statistically significant suppression of CRP, PGE(2, )and MMP-3 in comparison with those of HA group. Inhibition of serum CRP was only observed in LI-HA group. The order of serum MMP-3 inhibition was LI-HA>HI-HA>HA. Based on macroscopic and histological analyses of pannus formation, hyperplasia, inflammation, joint leakage and erosion, and loss of proteoglycan, the only statistically significant improvement was shown in LI-HA group compared to HA group and HI-HA group compared to control group. ------>tmu_sno=None ------>sno=16827 ------>authors2=Sheu MT ------>authors3=Tsai WC ------>authors4=Lin YH ------>authors5=Li JL ------>authors6=Liang YC, Chang CC, Hsieh MS, Chen CH ------>authors6_c= ------>authors=Lo YJ ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Intra-articular injection of hyaluronate and indomethacin in rabbits with antigen-induced arthritis. ------>language=1 ------>check_flag=None ------>submit_date=None ------>country=None ------>no= ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2007 ------>submit_flag=None ------>publish_month=1 |