Taipei Medical University

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Seow KM
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------>journal_name=Gynecol Endocrinol
------>paper_name=Subtle progesterone rise in single dose gonadotropin-releasing hormone antagonist cycles Cetrorelix undergoing in vitro fertilization or intracytoplasmic sperm injection cycles
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------>fullAbstract=OBJECTIVE: To estimate the live-birth and miscarriage rates in 1-year age increments for women aged >/=40 years undergoing in vitro fertilization or intracytoplasmic sperm injection (ICSI-IVF) with autologous oocytes. DESIGN: Retrospective database and chart analysis. SETTING: Egyptian IVF and embryo transfer center. PATIENT(S): 1645 women aged >/=40 years undergoing 2004 fresh nondonor IVF-ICSI cycles. INTERVENTION(S): ICSI-IVF using ejaculate or surgically retrieved sperm. MAIN OUTCOME MEASURE(S): Pregnancy and live-birth rates per initiated cycle based on 1-year age increments. RESULT(S): The overall live-birth rate per initiated cycle was 6.7% (range: 10% to 0.5%). The pregnancy loss rate was 44.8% (range: 39.0% to 75.0%). The cutoff age was 43 years, when the pregnancy rate became statistically significantly lower. The live-birth rate per initiated cycle was statistically significantly higher for women <43 years old, 132 out of 1766 (7.4%) compared with women >/=43 years old, 7 out of 620 (1.1%). The miscarriage rate was 127 out of 295 (43.1%) compared with 15 out of 23 (65.2%) for the two age groups, respectively. CONCLUSION(S): The success rate of ICSI-IVF as measured by live-birth rate per initiated cycle was statistically significantly higher for women aged <43 years as compared with women aged >/=43 years. Once women have attained age 43 years, alternative methods such as oocyte donation cycles or previously cryopreserved embryos are likely to be more effective.
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------>authors2=Lin YH
------>authors3=Huang LW
------>authors4=Hsieh BC
------>authors5=Huang SC
------>authors6=Chen CY,Chen PH,Tzeng CR,Hwang JL
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------>authors=Seow KM
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------>updateTitle=Analysis of 2386 consecutive cycles of in vitro fertilization or intracytoplasmic sperm injection using autologous oocytes in women aged 40 years and above.
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------>no=6
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------>publish_year=2007
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z