| Li CS |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=0.711 ------>paper_class3=2 ------>paper_class2=1 ------>vol=32 ------>confirm_bywho=wingchan ------>insert_bywho=wingchan ------>Jurnal_Rank=86.9 ------>authors4_c= ------>comm_author=1 ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2=127 ------>medlineContent= ------>unit=E0119 ------>insert_date=20080321 ------>iam=7 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN=0899-7071 ------>authors_c= ------>score=500 ------>journal_name=Clinical imaging ------>paper_name=Differentiation of soft tissue benign and malignant peripheral nerve sheath tumors with magnetic resonance imaging. ------>confirm_date=20080325 ------>tch_id=085026 ------>pmid=18313576 ------>page1=121 ------>fullAbstract=PURPOSE: The objective of this study was to differentiate the magnetic resonance (MR) imaging appearance of benign peripheral nerve sheath tumors (PNSTs) from that of malignant PNSTs. MATERIALS AND METHODS: Twenty-six patients who underwent MR imaging and had a histologic diagnosis of benign (schwannoma, n=16; neurofibroma, n=1) or malignant (n=9) PNST were retrospectively reviewed. The size, location, shape, margin, and signal intensities of the tumors on precontrast and gadolinium-enhanced MR imaging were analyzed. In each patient, the presence or absence of split fat, target, and fascicular signs was determined. RESULTS: The mean size of the benign PNSTs (3.4 cm, S.D.=2.5 cm) was significantly smaller than that of the malignant tumors (8.2 cm, S.D.=3.1 cm) (P<.001). Seventeen (65.4%) of the 26 tumors were spindle shaped or ovoid (12 benign and 5 malignant tumors). Contiguity with specific nerves was identified in 15 (88.2%) of the 17 benign PNSTs but in none of the malignant tumors (P<.05). Well-defined margins were noted in all 17 benign PNSTs but in only 3 (33.3%) of the 9 malignant tumors (P<.001). Five (55.6%) of the 9 malignant PNSTs but none of the benign tumors showed signal intensity change in adjacent soft tissue (P<.05). There was no significant difference in signal intensity between the benign and malignant tumors on T(1)-weighted, T(2)-weighted, and contrast-enhanced MR images. The split fat and target signs were present more frequently in the benign PNSTs than in the malignant PNSTs (P<.05).Conclusions: Benign and malignant PNSTs are often spindle shaped. Recognition of contiguity with adjacent nerves, a well-defined margin, and the presence of the split fat sign may suggest benignity. Imaging features suggestive of malignancy can be a larger size and an infiltrative margin. ------>tmu_sno=None ------>sno=17046 ------>authors2=Huang GS ------>authors3=Wu HD ------>authors4=Chen WT ------>authors5=Shih LS ------>authors6=Lii JM,Duh SJ, Chen RC, Tu HY, Chan WP. ------>authors6_c= ------>authors=Li CS ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Differentiation of soft tissue benign and malignant peripheral nerve sheath tumors with magnetic resonance imaging. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=2 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2008 ------>submit_flag=None ------>publish_month=3 |