| Hsu MI |
------>authors3_c=??? ------>paper_class1=1 ------>Impact_Factor=3.114 ------>paper_class3=2 ------>paper_class2=1 ------>vol=91 ------>confirm_bywho=None ------>insert_bywho=morri ------>Jurnal_Rank=10.5 ------>authors4_c=??? ------>comm_author=1 ------>patent_EDate=None ------>authors5_c=??? ------>publish_day=4 ------>paper_class2Letter=None ------>page2=74 ------>medlineContent= ------>unit=E0111 ------>insert_date=20080321 ------>iam=1 ------>update_date=None ------>author=??? ------>change_event=2 ------>ISSN= ------>authors_c=??? ------>score=500 ------>journal_name=Fertil Steril ------>paper_name=Inappropriate gonadotropin secretion in polycystic ovary syndrome ------>confirm_date=None ------>tch_id=067013 ------>pmid=18325508 ------>page1=1168 ------>fullAbstract=OBJECTIVE: To evaluate inappropriate gonadotropin secretion in women with polycystic ovary syndrome (PCOS). DESIGN: Retrospective study. SETTING: Academic tertiary center. PATIENT(S): A total of 373 women were classified into three groups: [1] healthy control women (n = 48); [2] women who were positive for PCOS risk factor; and [3] women with PCOS (n = 251). INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Gonadotropin levels, LH-FSH ratio, body mass index, and clinical and/or biochemical presentations of PCOS. RESULT(S): The area under the receiver operating characteristic curve, used to predict PCOS for the LH-FSH ratio, showed similar diagnostic performance to total T and average ovarian volume. The LH-FSH ratio exhibits greater observed accuracy than total T and average ovarian volume for evaluation of women with oligomenorrhea or anovulation. An LH-FSH ratio of >1 presented the best combination of sensitivity and specificity. Body mass index was positively correlated with total T in non-PCOS and PCOS groups; however, body mass index was negatively correlated with LH in PCOS but showed no correlation in non-PCOS subjects. CONCLUSION(S): The LH-FSH ratio is a valuable diagnostic tool in evaluating women with PCOS and oligomenorrhea or anovulation, and an LH-FSH ratio of >1 may be used as a decision threshold. The link between body mass index and LH may provide clues for further understanding the pathological milieu of PCOS. ------>tmu_sno=None ------>sno=17131 ------>authors2=Liou TH ------>authors3=Liang SJ ------>authors4=Su HW ------>authors5=Wu CH ------>authors6=Hsu CS ------>authors6_c=??? ------>authors=Hsu MI ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c=??? ------>publish_area=0 ------>updateTitle=Inappropriate gonadotropin secretion in polycystic ovary syndrome. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=4 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2009 ------>submit_flag=None ------>publish_month=4 |