Loh CH |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=1.934 ------>paper_class3=2 ------>paper_class2=1 ------>vol=60 ------>confirm_bywho=None ------>insert_bywho=antsz ------>Jurnal_Rank=34.3 ------>authors4_c= ------>comm_author= ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2= ------>medlineContent= ------>unit=000 ------>insert_date=20080422 ------>iam=4 ------>update_date=None ------>author=??? ------>change_event=1 ------>ISSN=1351-0711 ------>authors_c= ------>score=500 ------>journal_name=Occupational Environmental Medicine ------>paper_name=Haematological effects among silk screening workers exposed to 2-ethoxy ethyl acetate ------>confirm_date=None ------>tch_id=096036 ------>pmid=12937203 ------>page1=e7 ------>fullAbstract=BACKGROUND: 2-Ethoxy ethyl acetate (2-EEA) is a solvent with broad industrial and commercial applications. It has been reported to cause hematological toxicity, infertility, and teratogenesis. AIMS: To investigate the haematological effects in 2-EEA exposed workers. METHODS: Workers from one silk screening shop (n = 29), using 2-EEA as the major cleaning and printing solvent, were recruited as a high exposure group. Workers with indirect and non-exposure to 2-EEA (n = 56) were recruited as the comparison group. Venous blood was collected for blood routine examination. Air concentration of 2-EEA in this plant was measured by eight hour personal sampling. RESULTS: The geometric mean (GM) of air concentration of 2-EEA in the high exposure group was 7.41 ppm (range 1.35-16.5 pppm). The mean exposure of female workers (GM = 9.34 ppm) was significantly higher than that of male workers (GM = 4.87 ppm). The GM of air 2-EEA concentration in the comparison group was 0.07 ppm (range: non-detectable to 3.62 ppm, n = 26). The haemoglobin and haematocrit in the female high 2-EEA exposure workers were significantly lower than those of female workers in the comparison group. No difference was found between male 2-EEA high exposure and comparison group workers. The haemoglobin, haematocrit, and RBC count in the study population had a significant dose-response relation with air 2-EEA levels. CONCLUSION: Results suggest that 2-EEA is a haematological toxicant, which leads to anaemic status in high exposure female workers. ------>tmu_sno=None ------>sno=18179 ------>authors2=Liou TS ------>authors3=Lin YC ------>authors4=Hsieh AT ------>authors5=Chen CY ------>authors6=Liao GD ------>authors6_c= ------>authors=Loh CH ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Haematological effects among silk screening workers exposed to 2-ethoxy ethyl acetate. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no= ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2003 ------>submit_flag=None ------>publish_month=1 |