Taipei Medical University

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Tsai TC
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------>journal_name=J Med Edu.
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------>fullAbstract=Background. Fastidious bacteria have been associated with bacterial vaginosis (BV) using PCR methods. We assessed the prevalence of these bacteria in HIV-1 infected women and their relationship with vaginal pH and shedding of HIV-1 RNA. Methods. 64 cervicovaginal lavage (CVL) samples were collected from 51 women. Vaginal microbiota were characterized using 8 bacterium-specific quantitative PCR assays. Results. Women with the fastidious bacteria Bacterial Vaginosis Associated Bacterium (BVAB) 1, 2, and 3 showed a trend to increased HIV-1 shedding (OR 2.59-3.07, P = .14-.17). Absence of Lactobacillus crispatus (P < .005) and presence of BVAB2 (P < .001) were associated with elevated vaginal pH. BVAB1, 2, and 3 were highly specific indicators of BV in HIV-infected women, with specificities of 89%-93%. Conclusions. Fastidious bacteria (BVAB 1, 2, and 3) remain specific indicators of BV in HIV-infected women, and BVAB2 may contribute to the elevated vaginal pH that is a hallmark of this syndrome.
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------>authors=Tsai TC
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------>updateTitle=Detection of Fastidious Vaginal Bacteria in Women with HIV Infection and Bacterial Vaginosis.
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------>no=10
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------>publish_year=2006
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z