| Wu CC |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=1.435 ------>paper_class3=2 ------>paper_class2=1 ------>vol=23 ------>confirm_bywho=None ------>insert_bywho=m102093020 ------>Jurnal_Rank=63.6 ------>authors4_c= ------>comm_author= ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2=941 ------>medlineContent= ------>unit=E0121 ------>insert_date=20080729 ------>iam=5 ------>update_date=None ------>author=??? ------>change_event=2 ------>ISSN= ------>authors_c= ------>score=500 ------>journal_name=Eur J Anaesth ------>paper_name=Doxapram and aminophylline on bispectral index under sevoflurane anaesthesia: a comparative study. ------>confirm_date=None ------>tch_id=095126 ------>pmid=16895622 ------>page1=937 ------>fullAbstract=BACKGROUND AND OBJECTIVE: To evaluate and compare the effect of two clinically available central nervous system stimulants, namely doxapram and aminophylline on arousal from sevoflurane anaesthesia and bispectral index. METHODS: This randomized, double-blind, placebo-controlled, prospective study was conducted in 90 adult females, ASA I-II, scheduled for elective lower abdominal surgeries at Taipei Medical University Hospital. At 5 min before the completion of surgery, under sevoflurane anaesthesia, patients were divided into three groups to receive doxapram 1 mg kg(-1), aminophylline 2 mg kg(-1) or saline placebo intravenous. Standard vital signs, end-tidal CO(2), end-expiratory sevoflurane concentration, bispectral index and neuromuscular blockade were measured plus clinical parameters of recovery from general anaesthesia. RESULTS: Compared with the control group, patients receiving doxapram or aminophylline showed a similarly faster recovery from sevoflurane anaesthesia correlated with increase in bispectral index. CONCLUSION: Intravenous administration of doxapram 1 mg kg(-1) or aminophylline 2 mg kg(-1) hastened the early recovery from sevoflurane anaesthesia. The arousal effect of aminophylline and doxapram appears to be similar. ------>tmu_sno=None ------>sno=18747 ------>authors2=Lin CS ------>authors3=Wu GJ ------>authors4=Lin YH ------>authors5=Lee YW ------>authors6=Chen JY, Mok MS ------>authors6_c= ------>authors=Wu CC ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Doxapram and aminophylline on bispectral index under sevoflurane anaesthesia: a comparative study. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no= ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2006 ------>submit_flag=None ------>publish_month=8 |