Shih Ming Chen |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=1.663 ------>paper_class3=2 ------>paper_class2=1 ------>vol=22 ------>confirm_bywho=1 ------>insert_bywho=anbangwu ------>Jurnal_Rank=48.6 ------>authors4_c= ------>comm_author=1 ------>patent_EDate=None ------>authors5_c= ------>publish_day=23 ------>paper_class2Letter=None ------>page2=1012 ------>medlineContent= ------>unit=G0100 ------>insert_date=20081119 ------>iam=7 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN= ------>authors_c= ------>score=500 ------>journal_name=BIOMEDICAL CHROMATOGRAPHY ------>paper_name=Separation and structure determination of nicardipine photoproducts by LC-ESI-MS ------>confirm_date=None ------>tch_id=065001 ------>pmid=18651604 ------>page1=1008 ------>fullAbstract=A sample of 0.104 M nicardipine in methanol was photoirradiated with a Philips 400 W UV lamp for 3 h in a photochemical chamber. A total of four major photoproducts were found from the HPLC chromatogram. The same sample was used for taking LC-MS, while eight major photoproducts were observed and the structures elucidated by analyzing the CID patterns of their respective mass spectra. A reaction scheme of nicardipine is proposed that the photochemical reactions occur mainly via oxidation of 1,4-dihydropyridine moiety, following the stepwise photo-reduction of the m-nitro group and demethylation of the ester group at 5-position of the pyridine ring. ------>tmu_sno=None ------>sno=19340 ------>authors2=Mau Chih Hsieh ------>authors3=Su Hui Chao ------>authors4=E. E. Chang ------>authors5=Po Yu Wang ------>authors6=An Bang Wu ------>authors6_c= ------>authors=Shih Ming Chen ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Separation and structure determination of nicardipine photoproducts by LC-ESI-MS. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no= ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2008 ------>submit_flag=None ------>publish_month=7 |