Lau LI |
------>authors3_c=??? ------>paper_class1=1 ------>Impact_Factor=2.628 ------>paper_class3=2 ------>paper_class2=1 ------>vol=146 ------>confirm_bywho=wmhsu ------>insert_bywho=wmhsu ------>Jurnal_Rank=22.2 ------>authors4_c=??? ------>comm_author= ------>patent_EDate=None ------>authors5_c=??? ------>publish_day=1 ------>paper_class2Letter=None ------>page2=578 ------>medlineContent= ------>unit=E0115 ------>insert_date=20081120 ------>iam=7 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN= ------>authors_c=??? ------>score=500 ------>journal_name=American Journal of Ophthalmology ------>paper_name=Intraocular pressure elevation after intravitreal triamcinolone acetonide injection in a Chinese population ------>confirm_date=20081124 ------>tch_id=096076 ------>pmid=18639860 ------>page1=573 ------>fullAbstract=PURPOSE: To study the prevalence and risk factors of intraocular pressure (IOP) elevation and refractory IOP elevation after a single 4 mg intravitreal triamcinolone acetonide (IVTA) injection in a Chinese population. DESIGN: Retrospective, observational case series. METHODS: Retrospective chart review of all the patients who received an IVTA injection at one medical center from January 2003 through June 2005. A postoperative IOP increase of more than 6 mm Hg was defined as an IOP elevation. Postoperative IOP elevation that could not be controlled by glaucoma medications was defined as refractory IOP elevation. RESULTS: Sixty-four (43.5%) of the 147 enrolled patients experienced IOP elevation. Males had a higher risk of IOP elevation, with an odds ratio (OR) of 3.17 (95% confidence interval [CI], 1.38 to 7.27; P = .006), after adjusting for age, glaucoma history, and diagnosis of retinal disease. Patients 55 years of age and younger had a larger magnitude of IOP elevation than those older than 55 years (11.2 +/- 10.1 mm Hg vs 7.3 +/- 7.7 mm Hg; P = .020). Ten patients (6.8%) had refractory IOP elevation, and those 55 years of age or younger had a higher risk of refractory IOP elevation compared with those older than 55 years, with an OR of 8.16 (95% CI, 1.67 to 39.81; P = .009), after adjusting for preoperative IOP and diagnosis of retinal disease. CONCLUSIONS: Elevated IOP after IVTA injection is common in this Chinese population. Male patients have a higher risk of IOP elevation. Younger patients should be monitored carefully after IVTA injection because they exhibit a greater magnitude of IOP elevation and have an increased chance of developing refractory IOP elevation. ------>tmu_sno=None ------>sno=19567 ------>authors2=Chen KC ------>authors3=Lee FL ------>authors4=Chen SJ ------>authors5=Ko YC ------>authors6=Liu CJL, Hsu WM ------>authors6_c=???, ??? ------>authors=Lau LI ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c=??? ------>publish_area=0 ------>updateTitle=Intraocular pressure elevation after intravitreal triamcinolone acetonide injection in a Chinese population. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=10 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2008 ------>submit_flag=None ------>publish_month=10 |