Taipei Medical University

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Chen MJ
------>authors3_c=???
------>paper_class1=1
------>Impact_Factor=1.034
------>paper_class3=2
------>paper_class2=1
------>vol=23
------>confirm_bywho=None
------>insert_bywho=wmhsu
------>Jurnal_Rank=71.1
------>authors4_c=???
------>comm_author=
------>patent_EDate=None
------>authors5_c=
------>publish_day=1
------>paper_class2Letter=None
------>page2=566
------>medlineContent=
------>unit=000
------>insert_date=20081202
------>iam=4
------>update_date=None
------>author=???
------>change_event=2
------>ISSN=
------>authors_c=???
------>score=500
------>journal_name=J Ocul Pharmacol Ther
------>paper_name=Comparison of the effects of latanoprost and bimatoprost on intraocular pressure in chronic angle-closure glaucoma.
------>confirm_date=None
------>tch_id=096076
------>pmid=18001247
------>page1=559
------>fullAbstract=PURPOSE: The aim of this study was to compare the intraocular pressure (IOP)-lowering effect of latanoprost and bimatoprost as primary therapy in patients with chronic angle-closure glaucoma (CACG) after peripheral iridotomy. METHODS: Eighty-two (82) consecutive CACG patients with an IOP greater than 19 mmHg after a peripheral iridotomy were recruited. CACG was defined as chronic elevated IOP, glaucomatous optic neuropathy, and a corresponding visual field defect in eyes with occludable angle and peripheral anterior synechiae on gonioscopy. Patients were randomly assigned to two groups based on daily treatment with either latanoprost 0.005% or bimatoprost 0.03% in the evening for 12 weeks. The IOP was measured at 9 AM and 4 PM on the same day at baseline and also at 4, 8, and 12 weeks. Between-group differences in mean diurnal IOP and IOP reduction were analyzed. RESULTS: After 12 weeks of treatment, mean IOP for both the latanoprost and bimatoprost groups was significantly reduced when compared to the baseline value (21.6 +/- 1.9 to 16.4 +/- 2.5 mmHg and 22.1 +/- 2.0 to 16.9 +/- 2.4 mmHg, respectively; P < 0.001 for both). There was no significant difference in IOP reduction between the two treatment groups (P = 0.40). At 4 and 8 weeks, the IOP changes from baseline were statistically significant at both times for both drugs (all P < 0.001). CONCLUSIONS: Both latanoprost and bimatoprost significantly reduced IOP in CACG patients who were inadequately treated by laser peripheral iridotomy.
------>tmu_sno=None
------>sno=20406
------>authors2=Cheng CY
------>authors3=Chou CK
------>authors4=Hsu WM
------>authors5=
------>authors6=
------>authors6_c=
------>authors=Chen MJ
------>delete_flag=0
------>SCI_JNo=None
------>authors2_c=???
------>publish_area=0
------>updateTitle=Comparison of the effects of latanoprost and bimatoprost on intraocular pressure in chronic angle-closure glaucoma.
------>language=2
------>check_flag=None
------>submit_date=None
------>country=None
------>no=6
------>patent_SDate=None
------>update_bywho=None
------>publish_year=2007
------>submit_flag=None
------>publish_month=12
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z