| Chen C-M |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=1.180 ------>paper_class3=2 ------>paper_class2=1 ------>vol=17 ------>confirm_bywho=sihuang ------>insert_bywho=clark ------>Jurnal_Rank=73.2 ------>authors4_c= ------>comm_author=1 ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2=414 ------>medlineContent= ------>unit=J0400 ------>insert_date=20081202 ------>iam=5 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN= ------>authors_c= ------>score=500 ------>journal_name=Asia Pac J Clin Nutr ------>paper_name=Consumption of purple sweet potato leaves decreases lipid peroxidation and DNA damage in humans ------>confirm_date=20081202 ------>tch_id=068001 ------>pmid=18818160 ------>page1=408 ------>fullAbstract=Consumption of polyphenols is associated with reduced risk of chronic diseases, possibly via a variety of bio-mechanisms, including antioxidation and anti-inflammation. Purple sweet potato leaves (PSPL) commonly consumed in Asia possess polyphenols. In this study, we aim to investigate antioxidant effect of 200 g/d PSPL containing 902 mg polyphenols in a clinical trial. This randomized, crossover clinical study included 16 healthy adults (7 M, 9 F; aged 20-22 y). After a 1-wk run period, subjects were assigned randomly to receive either PSPL or low polyphenol diet (LPD) for 2 wks, followed by a 2-wk washout period before crossing over to the alternate diet. Fasting blood and 24-h urine samples were collected from each subject at day 0, 7 and 14 of each phase. Our data showed PSPL consumption enhanced urinary total phenol excretion by 24.5% at day 14 as compared to day 0, while the LPD decreased total phenol content in plasma and urine by 3.3 and 16.3%, respectively (p< or =0.05). Low-density lipoprotein lag time and glutathione concentration in erythrocytes at day 14 was significantly enhanced by 15.0 and 33.3% by PSPL as compared to day 0, respectively, while their values were not altered by the LPD. Urinary 8-hydoxy-deoxyguanosine (8-OHdG) excretion decreased significantly by PSPL consumptoin by 36.7% at day 7 as compared to day 0, yet unchanged by the LPD (p< or =0.05). In conclusion, our results suggest that polyphenols in 200 g PSPL were bioavailable and could enhance antioxidant defense and decrease oxidative stress in young healthy people. ------>tmu_sno=None ------>sno=20416 ------>authors2=Lin Y-L ------>authors3=Chen CY ------>authors4=Hsu C-Y ------>authors5=Shieh M-J ------>authors6=Liu J-F ------>authors6_c= ------>authors=Chen C-M ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Consumption of purple sweet potato leaves decreases lipid peroxidation and DNA damage in humans. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=3 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2008 ------>submit_flag=None ------>publish_month=9 |