| Xi Wang |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=2.106 ------>paper_class3=2 ------>paper_class2=1 ------>vol= ------>confirm_bywho=leehorng ------>insert_bywho=hoyuansn ------>Jurnal_Rank=65.2 ------>authors4_c= ------>comm_author= ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2= ------>medlineContent= ------>unit=E0310 ------>insert_date=20081205 ------>iam=7 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN= ------>authors_c= ------>score=500 ------>journal_name=Cancer Investigation ------>paper_name=Reduced Expression of Tocopherol-Associated Protein (TAP/Sec14L2) in Human Breast Cancer ------>confirm_date=20090306 ------>tch_id=084007 ------>pmid=19909011 ------>page1= ------>fullAbstract=We show that TAP/Sec14L2 had a high expression in normal/benign breast, prostate, and liver tissues as compared to lung, colon, and kidney. Its expression was downregulated in breast cancer cell lines shown by quantitative-PCR. Further, 57% of 141 human invasive breast carcinomas had no or markedly reduced TAP/Sec14L2 expression by immunohistochemical staining, and the rate increased to 80% in high grade invasive carcinomas (p < .01). This downregulation of TAP/Sec14L2 was also present in ductal carcinoma in situ (DCIS) associated with invasive carcinomas. These findings raise the possibility that TAP/Sec14L2 may serve as a tumor suppressor in breast carcinogenesis. ------>tmu_sno=None ------>sno=20485 ------>authors2=Jing Ni ------>authors3=Chen-Long Hsu ------>authors4=Sharlin Johnykutty ------>authors5=Ping Tang ------>authors6=Yuan-Soon Ho, Chia-Hwa Lee,and Shuyuang Yeh ------>authors6_c=???, ???, ??? ------>authors=Xi Wang ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Reduced expression of tocopherol-associated protein (TAP/Sec14L2) in human breast cancer. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no= ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2008 ------>submit_flag=None ------>publish_month=1 |