Chen LC |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=2.935 ------>paper_class3=2 ------>paper_class2=1 ------>vol=735 ------>confirm_bywho=amel ------>insert_bywho=llyang ------>Jurnal_Rank=21.4 ------>authors4_c= ------>comm_author= ------>patent_EDate=None ------>authors5_c= ------>publish_day=26 ------>paper_class2Letter=None ------>page2=40 ------>medlineContent= ------>unit=G0100 ------>insert_date=20081215 ------>iam=5 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN= ------>authors_c= ------>score=500 ------>journal_name=Journal of Chromatography B ------>paper_name=Pharmacokinetic study of paeoniflorin in mice after oral administration of Paeoniae radix extract ------>confirm_date=20081217 ------>tch_id=058001 ------>pmid=10630888 ------>page1=33 ------>fullAbstract=Quantification of paeoniflorin, the principal bioactive component of Paeoniae radix, in mice plasma following oral administration of Paeoniae radix extract was achieved by using a simple and rapid high-performance liquid chromatographic method. The calibration curve for paeoniflorin was linear (r2 = 0.998) over the concentration range 10-200 ng/ml. The coefficients of variation of intra- and inter-day assays were 15.04, 7.31, 6.14, 6.55, 6.63% and 12.71, 6.07, 3.61, 5.51, 4.52% at concentrations of 10, 60, 100, 160, 200 ng/ml, respectively. The recoveries of paeoniflorin from mice plasma were found to be 74.49, 76.83, 80.38 and 80.56% for concentrations of 30, 80, 120 and 160 ng/ml, respectively. The plasma concentration-time curves were fitted with mean terminal half-lives (t(1/2)) of 94.16 min. ------>tmu_sno=None ------>sno=20825 ------>authors2=Lee MH ------>authors3=Chou MH ------>authors4=Lin MF ------>authors5=Yang LL ------>authors6= ------>authors6_c= ------>authors=Chen LC ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Pharmacokinetic study of paeoniflorin in mice after oral administration of Paeoniae radix extract. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=1 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=1999 ------>submit_flag=None ------>publish_month=11 |