Jia-Wei Lin |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=1.112 ------>paper_class3=2 ------>paper_class2=1 ------>vol=66 ------>confirm_bywho=shtsai ------>insert_bywho=wtchiu ------>Jurnal_Rank=53.2 ------>authors4_c= ------>comm_author=1 ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2=S25 ------>medlineContent= ------>unit=E0110 ------>insert_date=20081216 ------>iam=4 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN= ------>authors_c= ------>score=126 ------>journal_name=Surgical Neurology ------>paper_name=Survey of traumatic intracranial hemorrhage in Taiwan ------>confirm_date=20091016 ------>tch_id=073010 ------>pmid=17880559 ------>page1=S20 ------>fullAbstract=The correlations between D-dimer and Glasgow Coma Scale (GCS), pupillary light reflex, distance of midline shift on brain computed tomography (CT), and Glasgow Outcome Score (GOS) in patients with trauma/non-trauma intracranial hemorrhage (ICH) are not consistent in studies. Ninety-eight traumatic and 59 non-traumatic ICH patients were studied. Pre-existing venous thrombosis, recent surgery, drug use (aspirin or coumadin), or malignancy, were excluded. D-dimer level was estimated within hours after acute insult, and statistical analyses were used for comparisons between groups. Traumatic ICH patients had higher D-dimer levels than controls (2984 vs. 256 microg/l; P = 0.001). The GCS, midline shift on brain CT, pupillary reflex, and GOS at 3 months were significantly correlated with high D-dimer value in traumatic patients (individual P < 0.001), but not in the non-traumatic group. Using receiver-operating characteristic curve (ROC), the cutoff point was 1496 microg/l, with sensitivity and specificity of 100% and 83%, respectively. D-dimer > or =1496 microg/l predicted a poor outcome [adjusted odds ratio (OR) 14.44, 95% CI 1.16-179.27; P = 0.038]. A high D-dimer level is associated with a poor outcome in patients with traumatic ICH. It can be used in addition to neurological assessment to predict the outcome. ------>tmu_sno=None ------>sno=20861 ------>authors2=Shih-Han Tsai ------>authors3=Wan-Chen Tsai ------>authors4=Wen-Ta Chiu ------>authors5=Shu-Fen Chu ------>authors6=Chien-Min Lin, Che-Ming Yang, Ching-Chang Hung ------>authors6_c= ------>authors=Jia-Wei Lin ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Correlation of a high D-dimer level with poor outcome in traumatic intracranial hemorrhage. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=Suppl2 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2006 ------>submit_flag=None ------>publish_month=1 |