Taipei Medical University

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Chung-Ching Hsie
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------>journal_name=Therapeutic Radiology and Oncology
------>paper_name=Mycosis Fungoides: A Case Report
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------>fullAbstract=Adult T-cell leukemia/lymphoma (ATL) is an aggressive type of leukemia/lymphoma associated with the human T-cell lymphotropic virus (HTLV-I). We describe an adult male patient clinically and pathologically diagnosed as mycosis fungoides and treated with chemotherapy after which complete involution of the lesions occurred. The disease relapsed with confluent dyshidrosis-like vesicles on the palmoplantar regions, followed by disseminated vesiculopapules and associated lymphocytosis. A serological test performed at this time revealed HTLV-I infection, and a diagnosis of chronic ATL was made. Monoclonal integration of HTLV-I was detected in peripheral blood mononuclear cells by inverse long polymerase chain reaction. A skin biopsy revealed spongiosis, Pautrier abscesses, and intraepidermal vesicles with atypical lymphocytes and an infiltration of small and atypical CD4 lymphocytes in the superficial dermis. Proliferative index (Ki-67) was 70%. This is the first reported vesicular cutaneous ATL with confirmation of HTLV-I proviral integration. The delay that occurred in diagnosing ATL was due to the fact that mycosis fungoides and ATL may present the same clinical, histopathological, and immunohistochemical features.
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------>authors2=Meng-Hao Wu
------>authors3=Yuen-Liang Lai
------>authors4=Hung-Cheng Chen
------>authors5=Cheng-I His
------>authors6=Kou-Hwa Chang, Chang-Hung Chung, Hung-Chi Dai
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------>authors=Chung-Ching Hsie
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------>updateTitle=A Dyshidrosis-Like Variant of Adult T-Cell Leukemia/Lymphoma With Clinicopathological Aspects of Mycosis Fungoides. A Case Report.
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------>publish_year=1999
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z