| ChenYH |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=5.783 ------>paper_class3=2 ------>paper_class2=1 ------>vol=00 ------>confirm_bywho=None ------>insert_bywho=yichen ------>Jurnal_Rank=5.5 ------>authors4_c= ------>comm_author= ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2=00 ------>medlineContent= ------>unit=J0200 ------>insert_date=20090415 ------>iam=1 ------>update_date=None ------>author=??? ------>change_event=2 ------>ISSN= ------>authors_c= ------>score=500 ------>journal_name=Archives of Neurology ------>paper_name=Affect of seizures during gestation on pregnancy outcomes in women with epilepsy ------>confirm_date=None ------>tch_id=090087 ------>pmid=19667219 ------>page1=00 ------>fullAbstract=OBJECTIVE: To assess whether seizures in women with epilepsy during pregnancy contribute to adverse pregnancy outcomes. DESIGN: A retrospective cross-sectional study. SETTING: Taiwan. Patients This study linked 2 nationwide population-based data sets: Taiwan~s birth certificate registry and the Taiwan National Health Insurance Research Data set. A total of 1016 women with epilepsy were selected who had single births from 2001 to 2003 and who had been diagnosed with epilepsy within 2 years prior to their index delivery, together with 8128 matched women without chronic disease as a comparison cohort. Women with epilepsy were further stratified into 2 groups for analysis: women who did and did not have seizures during pregnancy. MAIN OUTCOME MEASURES: Low-birth-weight infants, preterm delivery, and infants who are small for gestational age (SGA). RESULTS: Compared with women without epilepsy, epileptic seizures during pregnancy were independently associated with a 1.36-fold (95% confidence interval [CI], 1.01-1.88), 1.63-fold (95% CI, 1.21-2.19), and 1.37-fold (95% CI, 1.09-1.70) increased risk of low-birth-weight infants, preterm delivery, and SGA, respectively, after adjusting for family income and parental and infant characteristics. Further, the risk of SGA increased significantly (odds ratio, 1.34; 95% CI, 1.01-1.84) for women with seizures during pregnancy compared with women with epilepsy who did not have seizures during pregnancy. CONCLUSION: We suggest preventing seizures during pregnancy as an essential step to reduce risk of adverse pregnancy outcomes. ------>tmu_sno=None ------>sno=21775 ------>authors2=Chiou HY ------>authors3=Lin HC ------>authors4=Lin HL ------>authors5= ------>authors6= ------>authors6_c= ------>authors=ChenYH ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Affect of seizures during gestation on pregnancy outcomes in women with epilepsy. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=00 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2009 ------>submit_flag=None ------>publish_month=1 |