Chen YH |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=3.773 ------>paper_class3=2 ------>paper_class2=1 ------>vol=00 ------>confirm_bywho=None ------>insert_bywho=yichen ------>Jurnal_Rank=6.6 ------>authors4_c= ------>comm_author= ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2=00 ------>medlineContent= ------>unit=J0200 ------>insert_date=20090924 ------>iam=1 ------>update_date=None ------>author=??? ------>change_event=2 ------>ISSN= ------>authors_c= ------>score=500 ------>journal_name=Human Reproduction ------>paper_name=Increased Risk of Preterm Births among Women with Uterine Leiomyoma: A Nationwide Population-based Study. ------>confirm_date=None ------>tch_id=090087 ------>pmid=19740897 ------>page1=00 ------>fullAbstract=BACKGROUND: Using a 3-year nationwide population-based database, this study examines the risk of adverse pregnancy outcomes [lower birthweight, preterm gestation and babies small for gestational age (SGA)] in pregnant women with uterine leiomyoma. METHODS: This study linked two data sets: Taiwan~s birth certificate registry and its National Health Insurance Research Data set. A total of 5627 mothers with uterine leiomyoma and 28 135 unaffected mothers were included for analysis. After adjusting for mother and infant characteristics and monthly family income, log-binominal regression and multivariate regression analyses were conducted to examine the risks of preterm birth, SGA and lower birthweight among mothers with uterine leiomyoma and unaffected mothers. RESULTS: Women with uterine leiomyoma had a significantly higher percentage of preterm births (10.98 versus 7.78%, P < 0.001) and SGA infants (19.00 versus 17.28%, P = 0.002) than unaffected mothers. The mean birthweights for mothers with and without uterine leiomyoma were 3083 and 3172 g, respectively (P < 0.001). Log-binominal regression models show that the adjusted risk ratios of preterm births and SGA infants for mothers with uterine leiomyoma were 1.32 (95% CI 1.19-1.46) and 1.16 (95% CI 1.08-1.26), respectively, compared with unaffected mothers. After finally adjusting for gestational age and other covariates, a multivariate regression analysis revealed that women with uterine leiomyoma had, on average, a 14.7 g lower birthweight than unaffected mothers (P = 0.022). CONCLUSIONS: We concluded that after adjusting for potential confounders, women with uterine leiomyoma experience a small yet significant increased risk of preterm and SGA infants. We suggest that clinicians intensively monitor women with uterine leiomyoma during pregnancy. ------>tmu_sno=None ------>sno=22309 ------>authors2=Lin HC ------>authors3=Chen SF ------>authors4=Lin HC ------>authors5= ------>authors6= ------>authors6_c= ------>authors=Chen YH ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Increased risk of preterm births among women with uterine leiomyoma: a nationwide population-based study. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=00 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2009 ------>submit_flag=None ------>publish_month=1 |