| Chiu WT |
------>authors3_c=??? ------>paper_class1=1 ------>Impact_Factor=1.556 ------>paper_class3=2 ------>paper_class2=1 ------>vol=66 ------>confirm_bywho=shtsai ------>insert_bywho=cck.ns ------>Jurnal_Rank=42.6 ------>authors4_c=??? ------>comm_author= ------>patent_EDate=None ------>authors5_c=??? ------>publish_day=1 ------>paper_class2Letter=None ------>page2=42 ------>medlineContent= ------>unit=J0600 ------>insert_date=20091003 ------>iam=5 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN= ------>authors_c=??? ------>score=500 ------>journal_name=Surgical Neurology ------>paper_name=Multicenter evaluation of propofol for head-injured patients in Taiwan. ------>confirm_date=20091005 ------>tch_id=093088 ------>pmid=17071254 ------>page1=37 ------>fullAbstract=BACKGROUND: The present study was a multicenter, retrospective study which aimed to evaluate the efficacy of propofol, a new choice of pharmacotherapy in head-injured patients. METHODS: Head-injured patients admitted to 3 hospitals during the period from January 2003 to December 2004 were included in this clinical trial. Data on patients~ demographics, laboratory data, GCS score, ICP, CPP, concurrent medications, and therapeutic outcomes were collected. RESULTS: Among the 104 patients included, only 44 were given propofol. The average age was 40.8 +/- 22 years for all patients, with 41.91 +/- 20.41 and 43.48 +/- 23.19 years for the propofol group and nonpropofol group, respectively (P=.097). There was no significant difference in baseline GCS score between the 2 groups (5.86 +/- 1.84 vs 5.66 +/- 1.59, P=.729). Mean ICP for the first 3 days in the ICU was 17.23 +/- 9.0 mm Hg in the propofol group and 33.19 +/- 32.56 in the nonpropofol group, respectively (P=.017). Mean CPP for the first 5 days in the ICU was 71.10 +/- 15.32 mm Hg in the propofol group and 43.20 +/- 29.92 mm Hg in the nonpropofol group (P<.001). A higher survival rate was found in the propofol group (81.8% vs 46.7%, P<.001). CONCLUSIONS: The present study demonstrated that propofol improved the outcome in recovery phase of head-injured patients. ------>tmu_sno=None ------>sno=22404 ------>authors2=Lin TJ ------>authors3=Lin JW ------>authors4=Huang SJ ------>authors5=Chang CK ------>authors6=Chen HY ------>authors6_c=??? ------>authors=Chiu WT ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c=??? ------>publish_area=0 ------>updateTitle=Multicenter evaluation of propofol for head-injured patients in Taiwan. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=S2 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2006 ------>submit_flag=None ------>publish_month=11 |