Lee TH |
------>authors3_c= ------>paper_class1=1 ------>Impact_Factor=2.843 ------>paper_class3=2 ------>paper_class2=1 ------>vol=72 ------>confirm_bywho=amel ------>insert_bywho=cklee ------>Jurnal_Rank=6.7 ------>authors4_c= ------>comm_author=1 ------>patent_EDate=None ------>authors5_c= ------>publish_day=1 ------>paper_class2Letter=None ------>page2=0 ------>medlineContent= ------>unit=G0100 ------>insert_date=20091017 ------>iam=7 ------>update_date=None ------>author=??? ------>change_event=4 ------>ISSN= ------>authors_c= ------>score=500 ------>journal_name=Journal of Natural Products ------>paper_name=Constituents of Polyalthia longifolia var. pendula ------>confirm_date=20091020 ------>tch_id=091116 ------>pmid=19860383 ------>page1=0 ------>fullAbstract=Three new clerodane-type diterpenes, 6alpha,16-dihydroxycleroda-3,13-dien-15-oic acid (1), 6alpha,16-dihydroxycleroda-4(18),13-dien-15-oic acid (2), and 4alpha,18beta-epoxy-16-hydroxyclerod-13-en-15-oic acid (3), and four new protoberberine alkaloids, (-)-8-oxo-10-hydroxy-2,3,9-trimethoxyberberine (4), (-)-8-oxo-2,11-dihydroxy-3,10-dimethoxyberberine (5), (-)-8-oxo-11-hydroxy-2,3,9,10-tetramethoxyberberine (6), and (-)-8-oxo-2,10-dihydroxy-3,9,11-trimethoxyberberine (7), together with 11 known substances, were isolated from a methanol extract of the stems of Polyalthia longifolia var. pendula. The structures of 1-7 were elucidated on the basis of spectroscopic data analysis. Compounds were evaluated for their antiproliferative activities against A549 and MCF-7 cancer cells, and among the substances tested, only 16-oxo-cleroda-3,13-dien-15-oic acid (8) exhibited cytotoxicity. ------>tmu_sno=None ------>sno=22752 ------>authors2=Wang MJ ------>authors3=Chen PY ------>authors4=Wu TY ------>authors5=Wen WT ------>authors6=Tsai FY, Lee CK ------>authors6_c= ------>authors=Lee TH ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c= ------>publish_area=0 ------>updateTitle=Constituents of Polyalthia longifolia var. pendula. ------>language=2 ------>check_flag=None ------>submit_date=None ------>country=None ------>no=12 ------>patent_SDate=None ------>update_bywho=None ------>publish_year=2009 ------>submit_flag=None ------>publish_month=12 |