Jong YJ, Li H, Chang JG, Hsieh-Li HM, Lee HH, Lee CC, Wang NM, Tsai CH. |
------>authors3_c=None ------>paper_class1=1 ------>Impact_Factor=None ------>paper_class3=1 ------>paper_class2=1 ------>vol=16 ------>confirm_bywho=hansun ------>insert_bywho=hsiumei ------>Jurnal_Rank=None ------>authors4_c=None ------>comm_author= ------>patent_EDate=None ------>authors5_c=None ------>publish_day=None ------>paper_class2Letter=None ------>page2=116 ------>medlineContent= ------>unit=E0200 ------>insert_date=20010208 ------>iam=4 ------>update_date= ------>author=??? ------>change_event=5 ------>ISSN=None ------>authors_c=None ------>score=500 ------>journal_name=Kao Hsiung I Hsueh Ko Hsueh Tsa Chih. ------>paper_name=Analysis of an SMN gene-like DNA fragment ------>confirm_date=20010330 ------>tch_id=089001 ------>pmid=10846346 ------>page1=112 ------>fullAbstract=Part of a survival motor neuron (SMN) gene-like DNA fragment has been identified. This DNA fragment was accidentally isolated from cDNA by RT-PCR using primers specific for the region between exon 3 and 6 of the SMN gene. This fragment was used as a probe to hybridize the mRNA from several tissues, but we have been unable to detect any transcript of this SMN-like gene in these tissues. Thus, we have inferred this SMN gene-like fragment was a genomic product contaminant that was amplified in the reaction. Sequencing analysis of this fragment, which contains several stop codons, revealed a 74.6% nucleotide homology with the SMN gene. From these results, we believe that this DNA fragment is not a mutated form of SMN gene. Rather, it is an SMN-like pseudogene, which is variably present even in normal individuals. ------>tmu_sno=None ------>sno=2682 ------>authors2=None ------>authors3=None ------>authors4=None ------>authors5=None ------>authors6=None ------>authors6_c=None ------>authors=Jong YJ, Li H, Chang JG, Hsieh-Li HM, Lee HH, Lee CC, Wang NM, Tsai CH. ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c=None ------>publish_area=None ------>updateTitle=Analysis of an SMN gene-like DNA fragment. ------>language=2 ------>check_flag= ------>submit_date= ------>country=None ------>no=3 ------>patent_SDate=None ------>update_bywho= ------>publish_year=2000 ------>submit_flag= ------>publish_month=None |