| Lin, P.-Y., Shi, S.-J., Shu, H.-L., Chen, H.-F., Lin, C.-C., Liu, P.-C., Wang, L.-F. |
------>authors3_c=None ------>paper_class1=1 ------>Impact_Factor=None ------>paper_class3=2 ------>paper_class2=1 ------>vol=28 ------>confirm_bywho=chenctsu ------>insert_bywho=wanglf ------>Jurnal_Rank=None ------>authors4_c=None ------>comm_author=1 ------>patent_EDate=None ------>authors5_c=None ------>publish_day=None ------>paper_class2Letter=None ------>page2=272 ------>medlineContent= ------>unit=E0103 ------>insert_date=20010425 ------>iam=7 ------>update_date= ------>author=??? ------>change_event=5 ------>ISSN=None ------>authors_c=None ------>score=500 ------>journal_name=Bioorganic Chemistry ------>paper_name=A Simple Procedure for Preparation of N-Thiazolyl and N-Thiadiazolylcantharidinimides and Evaluation of Their Cytotoxicities against Human Hepatocellular Carcinoma Cells. ------>confirm_date=20020509 ------>tch_id=062001 ------>pmid=11133145 ------>page1=266 ------>fullAbstract=We made an effort to prepare effective cantharidinimides by heating the reactants 1 and 2a-j to 200 degrees C with toluene and triethylamine to provide 10 N-thiazolyl- and N-thiadiazolylcantharidinimides 3a-j in high yields of 48-91%. All of the synthetic compounds were tested for their capability to suppress growth of the human hepatocellular carcinoma cell lines, SK-Hep-1 and Hep 3B. The results showed that compound 3f was the most potent, and it was more cytotoxic than cantharidin. Copyright 2000 Academic Press. ------>tmu_sno=None ------>sno=3661 ------>authors2=None ------>authors3=None ------>authors4=None ------>authors5=None ------>authors6=None ------>authors6_c=None ------>authors=Lin, P.-Y., Shi, S.-J., Shu, H.-L., Chen, H.-F., Lin, C.-C., Liu, P.-C., Wang, L.-F. ------>delete_flag=0 ------>SCI_JNo=None ------>authors2_c=None ------>publish_area=None ------>updateTitle=A Simple Procedure for Preparation of N-Thiazolyl and N-Thiadiazolylcantharidinimides and Evaluation of Their Cytotoxicities against Human Hepatocellular Carcinoma Cells. ------>language=2 ------>check_flag= ------>submit_date= ------>country=None ------>no= ------>patent_SDate=None ------>update_bywho= ------>publish_year=2000 ------>submit_flag= ------>publish_month=None |