Taipei Medical University

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Cherng YG, Huang HH, Chen TG and Huang CL.
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------>journal_name=Anaesthesia.
------>paper_name=The effect of cerebrospinal fluid dilution of isobaric 0.5% bupivacaine used for spianl anaesthesia.
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------>fullAbstract=A prospective study was conducted to see the effect on spinal anaesthesia of the dilution of isobaric 0.5% bupivacaine with cerebrospinal fluid. Sixty patients were randomly allocated to three groups. In group 1, patients received 3 ml isobaric 0.5% bupivacaine intrathecally without aspirating cerebrospinal fluid. In groups 2 and 3, cerebrospinal fluid 1 ml and 2 ml was aspirated respectively and mixed with 3 ml isobaric 0.5% bupivacaine. A total volume of 4 ml in group 2 and 5 ml in group 3 was administered. Thus, the volume of cerebrospinal fluid remained unchanged. Pinprick analgesia and motor block was evaluated from induction until recovery. No differences in onset time, duration and ~two segments regression~ were noticed. The only statistical difference was the time to reach complete motor block, which was shorter in group 1 as compared to groups 2 and 3 (6.9 SD 1.4 min versus 11.3 SD 3.0 and 13.5 SD 3.9 min respectively). The mean value of maximum decrease in systolic blood pressure was small, being less than 15% of the pre-operative value for each group. In conclusion, the effect of diluting isobaric 0.5% bupivacaine with cerebrospinal fluid, 1 ml and 2 ml, is minimal and it is an unnecessary procedure with limited clinical effect.
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------>authors=Cherng YG, Huang HH, Chen TG and Huang CL.
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------>updateTitle=The effect of cerebrospinal fluid dilution of isobaric 0.5% bupivacaine used for spinal anaesthesia.
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------>publish_year=1995
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z