Taipei Medical University

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Yang LM, Lin SJ. Hsu FL and Yang TH
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------>journal_name=Bioorganic & Medicinal Chemistry Letters
------>paper_name=Antitumor agents. part 3: synthesis and cytotoxicity of new trans-stilbene benzenesulfonamide derivatives
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------>fullAbstract=A new series of trans-stilbene benzenesulfonamide derivatives were designed and synthesized as potential antitumor agents. These new compounds were evaluated in the National Cancer Institute~s 60 human tumor cell line in vitro screen. Compounds 9-13 were cytotoxic against several cell lines. Notably, two compounds, 9 and 12, demonstrated selective cytotoxic activity against BT-549 breast cancer (GI(50)=0.205 microM) and HT-29 colon cancer (GI(50)=0.554 microM), respectively.
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------>authors=Yang LM, Lin SJ. Hsu FL and Yang TH
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------>updateTitle=Antitumor agents. Part 3: synthesis and cytotoxicity of new trans-stilbene benzenesulfonamide derivatives.
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------>publish_year=2002
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z