Taipei Medical University

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Chong CF, Li YC, Wang TL, Chang H
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------>journal_name=Journal of the American Medical Informatics Association, Supplement
------>paper_name=Stratification of Adverse Outcomes by Preoperative Risk Factors in Coronary Artery Bypass Graft Patients: An Artificial Neural Network Prediction Model
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------>fullAbstract=We constructed and internally validated an artificial neural network (ANN) model for prediction of in-hospital major adverse outcomes (defined as death, cardiac arrest, coma, renal failure, cerebrovascular accident, reinfarction, or prolonged mechanical ventilation) in patients who received "on-pump" coronary artery bypass grafting (CABG) surgery. We retrospectively analyzed a 5-year CABG surgery database with a final study population of 563 patients. Predictive variables were limited to information available before the procedure, and outcome variables were represented only by events that occurred postoperatively. The ANN~s ability to discriminate outcomes was assessed using receiver-operating characteristic (ROC) analysis and the results were compared with a multivariate logistic regression (LR) model and the QMMI risk score (RS) model. A major adverse outcome occurred in 12.3% of all patients and 18 predictive variables were identified by the ANN model. Pairwise comparison showed that the ANN model significantly outperformed the RS model (AUC = 0.886 vs.0.752, p = 0.043). However, the other two pairs, ANN vs. LR models (AUC = 0.886 vs. 0.807, p = 0.076) and LR vs. RS models (AUC = 0.807 vs. 0.752, p = 0.453) performed similarly well. ANNs tend to outperform regression models and might be a useful screening tool to stratify CABG candidates preoperatively into high-risk and low-risk groups.
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------>authors=Chong CF, Li YC, Wang TL, Chang H
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------>updateTitle=Stratification of adverse outcomes by preoperative risk factors in coronary artery bypass graft patients: an artificial neural network prediction model.
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------>publish_year=2003
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z