Taipei Medical University

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Cheng JJ
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------>journal_name=Radiology 1997
------>paper_name=The Use of Cardiovascular Ultrasound in Diagnosis of CAD.
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------>fullAbstract=INTRODUCTION: Endothelial dysfunction and inflammation play a key role in the development of atherosclerosis. The present study evaluated endothelial function, inflammatory parameters, and carotid intima-media thickness (IMT) in dyslipidemic patients with or without coronary artery disease (CAD). METHODS: Metabolic profile and inflammatory parameters were determined in dyslipidemic patients with (+CAD, n = 33) and without (-CAD, n = 69) symptomatic CAD. Endothelial function was evaluated by flow mediated dilatation (FMD) and plasma concentration of nitrites and nitrates. Carotid IMT was measured by ultrasound. RESULTS: No significant differences were observed in anthropometric hemodynamic or metabolic parameters between the groups. After adjusting by age and medication usage, some inflammatory markers were significantly higher in +CAD; however no significant differences in FMD or plasma levels of nitrites were observed. CONCLUSIONS: In subjects with dyslipidemia, the presence of CAD is associated with an elevation of certain inflammatory markers and carotid IMT but not with further endothelial dysfunction.
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------>authors=Cheng JJ
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------>updateTitle=Inflammation but not endothelial dysfunction is associated with the severity of coronary artery disease in dyslipidemic subjects.
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------>publish_year=1997
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z